Neuropharmacological Treatment of Mental Dysfunction in Parkinson’s Disease
نویسندگان
چکیده
منابع مشابه
Neuropharmacological Treatment of Mental Dysfunction in Parkinson’s Disease
Many patients with Parkinson's Disease (PD) experience significant cognitive and mood impairment -even early in the course of the disease. These mental impairments are only partially responsive to levodopa treatment and are often as disabling as the motor impairment, particularly in mid and late stages of the disease. Investigators have recently begun a search for new agents that can effectivel...
متن کامل[Mental dysfunction in Parkinson's disease].
In Parkinson's disease, mental disturbances frequently accompany the typical motor disorder. Subcortical dementia develops in 10 to 20% of patients. Contrary to the dementia of Alzheimer's type, the apraxia-aphasia-amnesia syndrome is uncommon. Depression and specific impairment of speech, visuospatial functions, and memory are present in an important proportion of patients. As a principal feat...
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The aim of the study was to investigate the efficacy of homemade tolcapone in treatment of patients with Parkinson's disease (PD). Eighty patients with PD were subjected to randomized, double-blind, placebo-controlled and parallel-group study. PD patients were randomly divided into the tolcapone treatment group (41 cases) and placebo group (39 cases). Each patient received 1 pill of tolcapone o...
متن کاملAutomatic, unsupervised classification of dyskinesia in patients with Parkinsons Disease
One of the characteristic symptoms of patients with Parkinson Disease (PD) is a rigidity of movement. These symptoms disappear after administration of Levodopa. However, the long-term use of levodopa causes involuntary movements (dyskinesia). A proper diagnosis requires an automatic, unsupervised method for the detection and classification of levodopa induced dyskinesia. The main problem, howev...
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ژورنال
عنوان ژورنال: Behavioural Neurology
سال: 2006
ISSN: 0953-4180,1875-8584
DOI: 10.1155/2006/138263